What should the nurse do first when the patient shows signs of an allergic reaction to Vancomycin?

In the event of a patient showing signs of an allergic reaction to Vancomycin, the most critical and immediate action for the nurse is to stop the infusion. This is important because continuing the infusion can exacerbate the allergic response, potentially leading to more severe reactions, such as anaphylaxis, which can be life-threatening. Stopping the infusion helps to prevent further exposure to the allergen and allows for timely intervention and management of the patient's symptoms.

Other subsequent steps may include notifying the healthcare provider, providing appropriate treatments such as antihistamines or corticosteroids if indicated, and closely monitoring the patient for any changes in their condition. While notification of the family and documentation of the reaction are important, they should occur after ensuring the patient’s safety through the immediate cessation of the medication. Prioritizing patient safety is essential in nursing practice, and stopping the infusion addresses this critical need first.